Latest Articles
Alpha and Beta Diversity in the Microbiome: How to Measure and Interpret Microbial Diversity
Alpha and beta diversity are essential metrics in microbiome research. They quantify microbial richness, evenness, and how communities differ across…
How to Submit Proteomics Data to PRIDE: A Practical Guide
Submitting proteomics data to the PRIDE repository is a mandatory requirement for publication in most journals — yet it is…
How to Assess MAG Quality: CheckM2, GUNC and What the Numbers Mean
You have run your binning pipeline and recovered a set of metagenome-assembled genomes (MAGs). Now comes a critical question: how…
How to Interpret DESeq2 Results
Running DESeq2 is the straightforward part. Understanding what the output actually means — and avoiding the mistakes that lead to…
Bacterial Genome Sequencing: Illumina vs Nanopore vs PacBio (Complete Guide for 2026)
Learn the differences among Illumina, Nanopore and PacBio for bacterial genome sequencing. Compare accuracy, read length, cost and application
How to Choose a Bioinformatics Service Provider
Sequencing data are easier to generate than ever, but analyzing them correctly remains difficult. Many research groups now receive FASTQ…
How to Interpret Differential Gene Expression Results
Differential gene expression analysis is one of the most common outputs of RNA-seq experiments. After running tools such as DESeq2,…
Low-Quality MAGs: Common Causes and Fixes
Metagenome-assembled genomes, or MAGs, are one of the most useful outputs of shotgun metagenomics. Instead of only asking which organisms…
Kraken2 vs Kaiju vs MetaPhlAn: Which Taxonomic Profiler Should You Use?
Taxonomic profiling is one of the most common tasks in shotgun metagenomics. After sequencing a microbiome or environmental sample, one…
Common DESeq2 Mistakes and How to Avoid Them
DESeq2 is one of the most widely used tools for differential gene expression analysis in RNA-seq experiments. It is powerful,…